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Lexicon Pharmaceuticals, Inc. (LXRX)

Nasdaq · Pharmaceutical Preparations · Manufacturing · CIK 1062822 · fiscal year ends in Dec

Closing price $1.49 on 29 Oct 2026; 52-week range $1.14 to $2.64.

Key figures

The last twelve months reported, with the latest price and balance sheet.

Revenue, last twelve months
$41.5M
Revenue growth
-29.0%
Net income, last twelve months
-$61.1M
Earnings per share
-$0.15
Gross margin
99.1%
Operating margin
-131.4%
Net margin
-147.4%
Return on equity
-35.0%
Market value
$665.8M
Cash
$40.9M
Debt
$51.4M
Debt to equity
0.29
Shares outstanding
446.9M

Financial statements

Revenue, profit and cash flow by fiscal year, each year linked to its annual report.

Fiscal yearYear endRevenueOperating incomeNet incomeEPSFree cash flowFiling
FY202531 Dec 2025$49.8M-$48.9M-$50.3M-$0.14-$67.9M10-K filed 5 Mar 2026
FY202431 Dec 2024$31.1M-$197.1M-$200.4M-$0.63-$179.8M10-K filed 7 Mar 2025
FY202331 Dec 2023$1.2M-$171.8M-$177.1M-$0.80-$162.4M10-K filed 25 Mar 2024
FY202231 Dec 2022$139.0K-$100.8M-$101.9M-$0.62-$90.2M10-K filed 3 Mar 2023
FY202131 Dec 2021$298.0K-$87.1M-$87.8M-$0.60-$88.2M10-K filed 10 Mar 2022

By quarter

QuarterQuarter endRevenueNet incomeEPS
Q2 FY202630 Jun 2026$692.0K-$31.8M-$0.07
Q1 FY202631 Mar 2026$21.1M-$1.0M$0.00
Q4 FY202531 Dec 2025$5.5M-$15.5M-$0.04
Q3 FY202530 Sep 2025$14.2M-$12.8M-$0.04
Q2 FY202530 Jun 2025$28.9M$3.3M$0.01
Q1 FY202531 Mar 2025$1.3M-$25.3M-$0.07
Q4 FY202431 Dec 2024$26.6M-$33.8M-$0.09
Q3 FY202430 Sep 2024$1.8M-$64.8M-$0.18

Revenue by segment

As the company reports it in the segment note of its annual report.

By product, FY2025

SegmentRevenueShare
License$45.0M90.6%
Product$4.6M9.4%

Company events

The newest 8-K filings of 243 held.

FiledFormEventItems
6 Aug 20268-KResults2.02, 9.01
7 May 20268-KResults2.02, 9.01
6 May 20268-KMaterial agreement, New debt, Share sale, Investor update1.01, 2.03, 3.02, 7.01, 9.01
30 Apr 20268-KMaterial agreement, Share sale, Shareholder vote, Bylaws or fiscal year change1.01, 3.02, 5.03, 5.07, 9.01
5 Mar 20268-KResults2.02, 9.01
2 Feb 20268-KMaterial agreement, Share sale, Shareholder rights change, Bylaws or fiscal year change, Investor update1.01, 3.02, 3.03, 5.03, 7.01, 9.01
29 Jan 20268-KResults, Investor update, Other events2.02, 7.01, 8.01, 9.01
10 Nov 20258-KOther events8.01
6 Nov 20258-KOther events8.01, 9.01
6 Nov 20258-KResults2.02, 9.01
6 Aug 20258-KResults2.02, 9.01
28 Jul 20258-KOther events8.01

Every filing

The newest filings with the SEC of 584 held.

FiledFormPeriod
14 Aug 2026EFFECT–
6 Aug 2026S-3–
6 Aug 2026S-8–
6 Aug 202610-Q30 Jun 2026
6 Aug 20268-K6 Aug 2026
7 May 202610-Q31 Mar 2026
7 May 20268-K7 May 2026
6 May 20268-K4 May 2026
30 Apr 20268-K30 Apr 2026
16 Mar 2026ARS31 Dec 2025
16 Mar 2026DEFA14A–
16 Mar 2026DEF 14A16 Mar 2026

Insider trades

Form 4 trades by officers, directors and 10% owners, last 12 months.

TradedInsiderTypeSharesPriceValueHeld afterForm 4
25 Feb 2026Debbane Raymond, DirectorPurchase2,000$1.49$3.0K1,906,18627 Feb 2026
23 Feb 2026Debbane Raymond, DirectorPurchase100,000$1.47$147.0K1,904,18625 Feb 2026
20 Feb 2026Debbane Raymond, DirectorPurchase100,000$1.48$147.8K1,804,18623 Feb 2026
19 Feb 2026Debbane Raymond, DirectorPurchase50,000$1.44$72.0K1,704,18623 Feb 2026
18 Feb 2026Debbane Raymond, DirectorPurchase133,688$1.32$176.5K1,654,18618 Feb 2026
17 Feb 2026Debbane Raymond, DirectorPurchase76,857$1.31$100.5K1,520,49818 Feb 2026
13 Feb 2026Debbane Raymond, DirectorPurchase57,952$1.31$75.9K1,443,64118 Feb 2026
2 Feb 2026Invus Global Management, Llc, DirectorPurchase1,538,462$1.30$2.0M1,538,4624 Feb 2026

Large holders

Schedule 13D and 13G filings by holders of more than 5% of the voting shares.

FiledHolderScheduleStakeShares
6 Aug 2026FMR LLC13G amended11.7%51.8M
8 May 2026Invus, L.P.13D amended39.4%175.2M
2 Feb 2026Invus, L.P.13D amended36.2%154.7M

Short interest

Shares sold short and not yet bought back, on each FINRA settlement date.

SettlementShares shortChangeDays to cover
15 Oct 202626.7M+3.39%12.97
30 Sep 202625.8M-10.3%6.16
15 Sep 202628.8M-2.36%13.4
31 Aug 202629.5M-9.95%10.28
14 Aug 202632.7M-0.23%10.93
31 Jul 202632.8M+0.29%12.46
15 Jul 202632.7M+6.32%12.03
30 Jun 202630.8M+21.08%4.44

Funds that hold it

From each fund's latest Form 13F.

180 funds held it at 30 Jun 2026: 80 added and 36 trimmed in the quarter. The largest:

FundSharesValueChange in the quarter
Artal Group S.A.175,156,062$420.4M+20,421,735
FMR LLC51,782,045$124.3M+6,725,707
Siren, L.L.C.44,303,518$106.3M0
Sessa Capital IM, L.P.18,960,836$45.5M+1,047,875
BlackRock, Inc.17,348,741$41.6M+14,026,522
Vanguard Capital Management LLC9,901,208$23.8M+382,041
Point72 Asset Management, L.P.8,251,325$19.8M+436,719
Geode Capital Management, LLC6,244,372$15.0M+3,075,261
State Street Corp.4,917,769$11.8M+3,953,731
Vanguard Portfolio Management LLC2,357,749$5.7M+1,811,149

Peers

Companies in the same industry.

  • Eli Lilly & Co. (LLY): revenue $86.5B, market value $1.29T
  • Johnson & Johnson (JNJ): revenue $99.3B, market value $662.4B
  • AbbVie Inc. (ABBV): revenue $64.4B, market value $513.9B
  • Merck & Co., Inc. (MRK): revenue $66.6B, market value $361.0B
  • Novartis AG (NVS): revenue $54.5B, market value $307.3B
  • AstraZeneca PLC (AZN): revenue $58.7B, market value $270.6B
  • Abbott Laboratories (ABT): revenue $46.6B, market value $180.9B
  • Novo Nordisk A/S (NVO): revenue $46.8B, market value $174.8B
  • Pfizer Inc. (PFE): revenue $63.7B, market value $170.7B
  • Vertex Pharmaceuticals Inc. (VRTX): revenue $12.6B, market value $136.8B
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